Former U.S. soldier John Rambo has settled into a peaceful retirement on his father's ranch after years of fighting and facing his PTSD. But the desire for revenge urges him to travel to Mexico, where he confronts a drug cartel. He quickly finds that his past has caught up with him. As the cartel chases him down, Rambo must use all his deadly combat skills to enact vengeance. With his trusty machete and bow, he prepares to draw the last blood for his final great mission.